Joints are areas that connect two bones in order to move parts of the body. They are usually composed of fibrous connective tissue and cartilage.Cartilage degrades with age and may even disappear completely, which can cause bone-to-bone contact in the joints, resulting in pain, stiffness, and sometimes swelling, and is a major cause of osteoarthritis.

There is currently no cure for osteoarthritis. Mainly with acetaminophen, ibuprofen, cortisone and other drugs to reduce pain, inflammation and suppress immunity, but there is side effects if long-term usage. In fact, there are many functional nutrients that can maintain good joint flexibility, reduce pain, strengthen bones, and have no side effects. As follows:

1.Curcumin

Curcumin has anti-inflammatory properties comparable to ibuprofen, diclofenac, or phenylbutazone, without the side effects of these NSaids. In a clinical trial to treat osteoarthritis, clinical studies have shown that the human body needs a high dose of at least 10 grams per day to reap the clinical benefits of nutrition,so turmeric needs very high doses to have an anti-inflammatory effect.

Kingherbs supply Curcumin extracted from natual turmeric root from Curcuminoid 1% to 95% HPLC .

2.Chondroitin sulfate

Chondroitin sulfate is a glycosaminoglycan found in connective tissue. First, It has metabolic activity for proteoglycan synthesis, because it is an important component of cartilage, but the amount in our body decreases with age, and it helps in the formation and maintenance of cartilage tissue by retaining moisture within the cartilage to ensure the flexibility and strength of the joint. Secondly, its anti-decomposition activity has an effect on induced inflammatory mediators and proteolytic enzymes. Therefore, it can reduce joint pain, slow the progression of osteoarthritis and repair affected joints.

3.Glucosamine

Glucosamine has two effective points, one is anabolic activity and the other is anti-decomposition activity. In terms of anabolic activity, it can synthesize proteoglycan, which is one of the main components of hyaluronic acid, present in joints and has the effect of lubricating them. In terms of anti-decomposition activity, it limits the action of IL-1β, inhibits type 2 prostaglandins by reducing the activity of COX-2, which reduces agglutinans and matrix metalloproteinases or collagenase.

4.Devil's Claw Extract

Devil's Claw is a natural herb grown in South Africa. It is extracted from the root and contains natural Harpagoside.The function of Devil's claw is attributed to its active ingredient Harpagoside and its superior efficacy, which has been around for thousands of years. Various studies have shown an improvement in symptoms associated with joint disease after just 4 weeks of treatment. In recent years, devil's claw has been widely used in Europe and the United States to relieve tendinitis, gout, inflammation, bone and joint pain, a pure natural, side-effect free herbal medicine. Human experiments have proved that after taking it, it can achieve anti-inflammatory effect and effectively relieve pain.

5.Collagen

Collagen is one of the most widely present protein forms in the human body. It is an important component of joints, tendons, ligaments, cartilage and skin.

Collagen is the most abundant protein in the body and is one of the main components of connective tissues such as tendons, ligaments, skin and cartilage. Collagen is known for its structural role in ensuring the cohesion of different tissues, giving them elasticity, resistance, flexibility, and allowing them to regenerate.

Collagen comes in 28 forms, of which type 2 is naturally present in the body and is the main structural protein in cartilage. Because type II collagen is a naturally occurring substance in the body, it is safe and well tolerated.

Joint disease is characterized by an autoimmune component that induces an immune system response against the type II collagen present in the body: the product of collagen degradation is recognized by immune cells as potentially dangerous, which then triggers an immune response to collagen, leading to inflammation and degeneration of cartilage, which further damages the joints. This phenomenon repeats, forming a vicious circle that is difficult to stop. Research suggests that supplementation with natural (undenatured) type II collagen may help regulate the immune response against endogenous Type II collagen, thereby promoting joint health.